Multiple Sites with Control Over All

[ncjbhd]

I've been told I can use PHP and MySQL to design a web site template that I can maintain administrative control over. This template needs to be repeated to dozens of users (and different domain names) that can maintain content management over specific areas. And I can make changes to all sites at one time by working with the template. Is this possible. And where do I go to learn how to bring this to life?