MySQL can’t even touch MS SQLServer's performance and power, especially with a properly set up multi-tiered, multi-server, multi-node, multi-cluster, and high availability setup. Also, with MS SQLserver you are already paying for SSIS, SSRS, and SSAS which are the best ETL tools, the easiest to use reporting tools, and by far the only tabular or multi-dimensional (cube) development framework that should ever be discussed.
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